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REMAP-CAP Trial: hydrocortisone and mortality in patients with severe community-acquired pneumonia
In a multinational adaptive trial of ICU patients with severe community-acquired pneumonia (CAP), a 7-day course of IV hydrocortisone (50 mg every 6 hours) was compared to no corticosteroids. Among 658 patients, 90-day mortality was higher in the hydrocortisone group (15% vs. 9.8%), with adjusted odds ratios between 1.52 and 1.63, all crossing ...
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