9H 15N 5O 3). Mol Chain Residues Atoms ZeroOcc AltConf 3 A 1 Total C N O 17 9 5 3 0 0 3 B 1 Total C N O 17 9 5 3 0 0 3 C 1 Total C N O 17 9 5 3 0 0 3 D 1 Total C N O 17 9 5 3 0 0 窶｢ Molecule 4 is …

2. General procedure for the synthesis of 3-ylideneoxindoles derivatives The 3-ylideneoxindoles were synthesized according to previously reported literature.1 An aqueous solution of NaOH (1.0 M, …

2-(4,5-Bis(((6-(2-ethoxy-2-oxoethoxy)quinolin-8-yl)amino)methyl)-6-hydroxy-3-oxo-3H-xanthen- 9-yl)benzoic acid (QZ2E, 3). 4′,5′-Fluoresceindicarboxaldehyde (43.9 mg, 113 μmol) and ethyl[(8- …

A mixture of 0.01 mole of 1-(4-hydrazono-6-methyl-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)quinolin-2(1H)-one (10) and 0.0l mole of aldehyde or ketone in (10 ml) absolute ethanol was refluxed in water …

Recent advancements in key technologies such as artificial intelligence (AI), big data, and the Internet of Things (IoT) have rapidly progressed, particularly in camera and display devices associated with …

ABSTRACT A series of novel dual A2A/A2B AR antagonists based on the triazole-pyrimidine-methylbenzonitrile core were designed and synthesised. The A2AAR antagonist cAMP functional …

Methods: Molecular fingerprint analysis was used for molecular partitioning of training and test sets. Acquired training sets were used for CoMFA and CoMSIA model construction after good alignment …