MODIFIED RANKIN SCALE(mRS) • 7-grade scale measuring functional independence and gait stability • mRShas been used to measure stroke outcomes and functional impact post-stroke • The scale is used a “core metric” of Comprehensive Stroke Centers; evaluating 90-day clinical outcomes of post-IV tPA

Jan 30, 2025 · Background: We investigate whether the NIHSS at 24 hours could serve as an alternative primary outcome measure in acute ischemic stroke trials, and whether combining 90-day modified Rankin Score (mRS) and 24-hour NIHSS in a hierarchical outcome could enhance detection of treatment effect, using EVT as an exemplary study intervention.

Despite advantages of modified National Institute of Health Stroke Scale and Scandinavian stroke scale comparing to the NIHSS, including their simplification and less inter-rater variability; most of the stroke neurologists around the world continue using the NIHSS.

Feb 19, 2025 · We investigate whether the National Institutes of Health Stroke Scale (NIHSS) at 24 hours could serve as a primary outcome in acute ischemic stroke trials, and whether combining 90‐day modified Rankin Scale (mRS) and 24‐hour NIHSS in a hierarchical outcome could enhance detection of treatment effect, using endovascular treatment (EVT) as an ...

Regulatory authorities favor functional outcome scales such as the modified Rankin Scale (MRS) or Barthel Index (BI),1 but they are crude and potentially insensitive measures of outcome after stroke. However, handicap and disability scales may …

Neurologic impairment scales such as the National Institutes of Health Stroke Scale (NIHSS) are possibly more sensitive to change in patient status. We aimed to compare a range of potential NIHSS end points with modified Rankin Scale (mRS) and Barthel Index (BI) end points.

The measures of functional outcome assessment scales, such as the modified Rankin scale (mRS) and the Barthel index (BI), are generally much simpler to administer and are much less graded than scales based on a neurological deficit.

Mar 9, 2019 · The NIHSS, mRS, and mTICI appear to be predictive tools of the functionality of the patient with ischemic stroke, especially in the acute phase. Rehabilitation demonstrates better results in reducing disability and greater participation of affected people.

Several scales have proven reliability and validity in stroke trials, including the National Institutes of Health stroke scale (NIHSS), the modified Rankin scale (mRS), the Barthel index (BI), the Glasgow outcome scale (GOS), and the stroke impact scale (SIS).

The modified Rankin scale (mRS) and Barthel index (BI) are widely used functional impairment and disability scales. Distinction between grades of mRS is poorly defined. The Asian stroke disability scale is a simplified functional impairment, handicap scale which is …