Topical non-steroidal anti-inflammatories (often abbreviated to NSAIDs) are creams, gels, rubs, solutions or sprays that contain a nonsteroidal anti-inflammatory agent and are designed to be …

Topical NSAIDs penetrate the skin and help reduce pain locally. They work best on joints that are closer to the surface, such as the hands, knees, elbows and ankles.

Apr 24, 2025 · Unlike oral NSAIDs, which reduce inflammation throughout your entire body, topical NSAIDs work to relieve pinpoint, localized pain and swelling in your joints, muscles and …

Jun 28, 2022 · Anti-inflammatory creams can help relieve pain from arthritis, shingles, and sprains. Discover how topical NSAIDs and other creams work, plus tips for application.

Sep 15, 2023 · We discuss topical NSAIDs and a variety of other treatments for painful, inflamed joints in our Guide to Alternatives for Arthritis. Many nondrug options carry fewer side effects …

Jul 17, 2025 · When your joints are painful or your muscles ache, topical painkillers -- those you apply to your skin -- may offer relief. You'll find many products for topical pain relief at your local...

Topical non‐steroidal anti‐inflammatory drugs (NSAIDs) are applied to unbroken skin where it hurts as gels, creams, sprays, or plasters. Topical NSAIDs penetrate the skin, enter tissues or …

May 17, 2025 · For older people or those who can't take this type of medicine by mouth, topical NSAIDs might be a good choice. Topical nonsteroidal anti-inflammatory creams and gels can …

Topical NSAIDs are nonsteroidal anti-inflammatory drugs designed for direct skin application over painful joints or muscles, offering localized pain relief with minimal systemic absorption.

In the United States, diclofenac is the only FDA approved topical NSAID and it is available in a few different formulations – an over-the-counter gel (Voltaren), a topical solution (PENNSAID) …