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DCx sees potential to build multifunctional ADCs using the same technology Repare used to create its small molecule synthetic lethal therapies.
The firm is studying the combination in the first-line setting for head and neck cancer patients who had a PD-L1 combined positive score of less than 1.
The biotech has nominated MB-111, a drug it's developing as a treatment for elevated triglycerides, as its first clinical development candidate.
Researchers at AACR discussed what's next for the drug class, given the disappointing activity of tiragolumab with Tecentriq ...
Pfizer Misses Revenue Expectations in Q1, But Invests Operational Savings in Oncology-Heavy Pipeline
The company said it took financial hits from the Inflation Reduction Act's Medicare Part D redesign, which included higher ...
Caring Cross, Wellbeing Foundation Africa Partner to Improve Access to Advanced Therapies in Nigeria
The nonprofit says its pipeline offers more affordable and accessible therapeutics, including point-of-care CAR-T cell therapy for leukemia and lymphoma.
The firm enrolled the first patient at Florida's BayCare Morton Plant Hospital, and the study procedure went according to protocol, per an investigator.
The firm is expecting Phase III readouts this year for its FGFR2b drug bemarituzumab and is advancing a second KRAS inhibitor to the clinic.
The clinical trial will include nearly 150 patients with advanced hepatocellular carcinoma that expresses glypican-3.
DCx will gain rights to technology, targets, and preclinical programs from Repare along with lab space and staff in Montreal.
In a Phase I study presented at AACR's annual meeting, 71 percent of patients who hadn't received a prior anti-HER2 ADC responded to the drug.
Most adults in the US would take a blood test to assess whether they will develop Alzheimer's, according to the survey, ...
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