Given that only a small fraction of patients with cancer exhibits specific markers making them eligible for effective targeted therapies, this paper investigates the justification of treating cancer ...

Centre for Social Ethics and Policy/Institute for Science, Ethics, and Innovation, School of Law, University of Manchester, Manchester, UK If you wish to reuse any or ...

Background Clinical papers so flawed that they are eventually retracted may put patients at risk. Patient risk could arise in a retracted primary study or in any secondary study that draws ideas or ...

Clarke’s arguments in favour of permitting conscientious objection (CO) in healthcare and setting up registries are not new, but the consequentialist basis for them and the careful attention to ...

There is a long history of medical research that involves intentionally infecting healthy people in order to study diseases and their treatments. Such research—what might be called “human challenge ...

The development of the fifth edition of the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders—the DSM-5—has reenergised and driven further forward critical ...

1 Department of Deontology and History of Medicine, Cukurova University, Adana, Turkey 2 Cukurova University Adana Health High School, Department of Midwifery, Adana, Turkey Correspondence to Dr Hasan ...

1 Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, Massachusetts, USA Objective To evaluate the relationship between recently trained paediatricians' ...

In an online study conducted separately in the UK and the US, participants rated the acceptability and fairness of four interventions: two types of financial incentives (rewards and penalties) and two ...

Colgrove and Rodger argue that the case advanced by Smajdor and Räsänen for classifying pregnancy as a disease can be defeated by an existence proof—that is, by identifying at least one plausible ...

NIEHS, National Institutes of Health, Research Triangle Park, North Carolina, USA Correspondence to Dr David B Resnik, NIEHS, National Institutes of Health, Research Triangle Park, Box 12233, Mail ...