Alignment.counts can take an aligner or substitution matrix to calculate the substitution score and positive matches (not identities). It would be nice if Alignment.format could do the same when ...

Abstract: Correlated mutations in proteins are believed to occur in order to preserve the protein functional folding through evolution. Their values can be deduced from sequence and/or structural ...

Overview of VAMP-seq datasets and proteins. (A) Structures of proteins previously studied with VAMP-seq coloured by average VAMP-seq abundance score per residue. Averages are shown for all residues ...

This valuable study presents a thorough analysis of protein abundance changes caused by amino acid substitutions, using structural context to improve predictive accuracy. By deriving substitution ...

How would you summarize your study for a lay audience? Our study introduces a new tool called FUSE (Functional Substitution Estimation) that helps scientists better understand how changes in genes ...

Sequence-based maximum likelihood (ML) phylogenetics is a widely used method for inferring evolutionary relationships, which has illuminated the evolutionary histories of proteins and the organisms ...

Warner Bros. is going back to the Matrix. The studio announced that a fifth “Matrix” movie is in development. It’ll be the first installment without Lana or Lily Wachowski as directors. Instead, “The ...

Warner Bros. is ready to re-enter The Matrix. A new "Matrix" film is in the works at Warner Bros. Pictures, with Drew Goddard ("The Cabin in the Woods") set to write and direct, the studio revealed on ...

Lana and Lilly Wachowski's landmark science-fiction film turns 25 this March. 1999 was famously a great year for film, and it’s hard to pick what masterpiece from that year stands out as the greatest.

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...