Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA ...

Tda1 protein kinase, activated by Snf1 and yeast GSK3-β, fine-tunes metabolism through the phosphorylation of Hxk2, which is implicated in yeast glucose repression. Tda1 is activated by both Snf1 and ...

MULGONET combines deep learning and multi-omics analysis to predict tumor recurrence, addressing interpretability and ...

Momentum Therapeutics Inc. has described receptor-interacting serine/threonine-protein kinase 3 (RIPK3) inhibitors reported to be useful for the treatment of systematic inflammatory response syndrome, ...

Srsf3 (serine/arginine-rich splicing factor 3)–mediated regulation of distal polyadenylation site selection in mitochondria-associated aminoacyl-tRNA synthetases facilitates the phagocytic maturation ...

Furthermore, PPA2 directly dephosphorylates NEDD4 at threonine 758 residue, resulting in its activation. Under hypoxic stress, NAD-dependent protein deacetylase sirtuin-5 promotes the dissociation of ...

L-Serine is considered a functional amino acid in the central nervous system, and induces sedation and hypnotic effects in some animal models of acute and chronic stress. Accordingly, while L-serine ...

View all available purchase options and get full access to this article. Carling D, Clarke PR, Zammit VA, Hardie DG. Purification and characterization of the AMP-activated protein kinase.

Although EOGT causes an atypical O-GlcNAcylation in endoplasmic reticulum, it also depends on hexosamine biosynthetic pathway (HBP) and UDP-GlcNAc to modify serine and threonine residues of target ...

Amino acids are the building blocks that form polypeptides and ultimately proteins. Consequently, they are fundamental components of our bodies and vital for physiological functions such as protein ...