The following reagents were purchased from the indicated manufacturers: rh IL-6, BAFF and SDF-1α from PEPROTECH EC (London, UK); rh TNFα, APRIL, IGF-1, VEGF, neutralizing mouse monoclonal ...

The most often studied kinases are protein kinases, which are generally subdivided into tyrosine, and serine/threonine-directed kinases. As such, kinases are key signal transduction molecules relevant ...

For example, the discovery of phosphorylation on tyrosine, a modification that was previously thought to occur exclusively on serine and threonine residues, was aided in part by extremely active ...