“In addition, we look forward to sharing translational data from preclinical studies in new indications such as anemia of inflammatory bowel disease (DISC-0974) and sickle cell disease (DISC-3405), ...

The digestive system plays an essential role in human health by managing nutrient intake, energy absorption, and waste excretion. Disorders within this system can lead to malnutrition and energy ...

Ulcerative colitis (UC) is a chronic gut inflammatory condition affecting the colon in humans. This study uses human samples as well as a mouse model of colitis induced by a chemical, DSS, to ...

This study uncovers the ketogenic diet's effects on the microbiome, revealing its potential to mitigate autoimmune diseases through metabolic pathways.

Vitamin D, the sunshine vitamin, plays a crucial role in calcium absorption, bone health, muscle function, and immune ...

A drug commonly used to treat glaucoma has been shown in zebrafish and mice to protect against the build-up in the brain of ...

Targeted, better-tolerated oral PDE4 inhibitors are an unmet need in inflammatory bowel disease (IBD) PALI-2108 demonstrates in ex vivo studies; targeted activation and reduced side effects, potential ...

As people live longer than ever before, the incidence of aging-related, chronic diseases is on the rise, severely impacting ...

The study emphasises on the role of the p53 tumor suppressor gene in the pathogenesis of ulcerative colitis - an inflammatory ...

Results provide a mechanistic explanation of why early loss of p53 signaling is frequently observed in UC-associated ...

The body can naturally produce vitamin D when skin is exposed to sunlight, but this process declines significantly in winter. | Cell And Molecular Biology ...