As a result, the surface of the eye develops permanent damage -- a condition called limbal stem cell deficiency. Worse, this damage can render the eye unfit for cornea replacement surgery ...

Stem cell therapy has emerged as a groundbreaking treatment option for corneal injuries, offering hope to individuals ...

Results of a phase I/II clinical trial of CALEC, limbal epithelial cell grafts generated by an innovative and rigorously standardized manufacturing protocol, showing safety and feasibility for ...

Patients with injuries that were previously considered untreatable have shown improvements in vision following stem cell ...

The cornea is made up of corneal epithelial stem cells that exist at the boundary ... a method for culturing autologous corneal limbal epithelial cell transplantation (CALEC), which has been ...

When these cells are lost because of injury or disease, it causes limbal stem cell deficiency. This can lead to lasting damage to the cornea and may cause blurred vision. CALEC involves a meticulous ...

The stem cell treatment for blinding cornea injuries — called cultivated autologous limbal epithelial cell (CALEC) transplantation — was developed at Mass Eye and Ear. It consists of removing stem ...

Since it’s on the frontline of potential hazards from the outside world, the cornea features a population of limbal epithelial stem cells, which repair minor damage to keep the surface smooth ...

The experimental therapy — called "cultivated autologous limbal epithelial cell transplantation" (CALEC) — works by taking stem cells from a patient's healthy eye, growing them into sheets of ...

The technique, developed by researchers at Dana-Farber Cancer Institute, Massachusetts Eye and Ear and Boston Children's Hospital, is called cultivated autologous limbal epithelial cells (CALEC). The ...

CALEC addresses a need for patients with limbal stem cell deficiency (LSCD), a condition that permanently damages the cornea, causes persistent pain and visual difficulties, and leaves patients ...

As a result, the surface of the eye develops permanent damage -- a condition called limbal stem cell deficiency. Worse, this damage can render the eye unfit for cornea replacement surgery ...