The traditional tool used to detect ANAs is indirect immunofluorescence. A new, automated test, the ELiA Symphony, detects antibodies against a mixture of nuclear and cytoplasmic antigens (ENAs ...

Anti-nuclear autoantibodies (ANA) are important biomarkers of systemic autoimmune ... For AAb screening in SARD, the indirect immunofluorescence assay (IFA) on human epithelial type 2 (HEp-2) cells is ...

Methods Twenty patients with seronegative scleromyositis diagnosed by expert opinion were analysed retrospectively for SSc features at myositis diagnosis and follow-up, and stratified based on HEp-2 ...

Methods: PBC specific ANA reactivity was tested by indirect immunofluorescence using HEp2 cells as substrate and individual Ig class (IgG, IgA, IgM) and IgG subclass (IgG1, IgG2, IgG3, IgG4) specific ...

[1] During the last decades, the use of HEp-2 cells as substrates for IIF has allowed the identification of ANA patterns which ... tested negative. IIF: Immunofluorescence; PBC: Primary biliary ...

You don’t just pay tax on your earnings and wealth – you’ll also pay indirect tax as part of your everyday, regular spending – but you might not realise it. These types of tax won’t come ...

Fluorescence is used in biology as a non-destructive way of analysing biological molecules, even at low concentrations, by means of the molecule’s intrinsic fluorescence, or by attaching it with ...

Our mission is to provide a state-of-the-art facility, expertise, and education in advanced quantitative light microscopy to support Drexel University’s research community The Cell Imaging Center (CIC ...

A thyroglobulin antibody (TgAb) test looks for certain antibodies that attack the thyroid. The presence of TbAb in high levels may indicate that someone has an autoimmune condition. To conduct a ...

Blood tests are often the first line of testing for evaluating MS symptoms. They can’t confirm a diagnosis of MS, but they can help rule out other conditions or point to a diagnosis. Multiple ...

The Task Force reported that many large commercial laboratories as well as some smaller hospital laboratories are not using the most accepted ANA screening by immunofluorescence (IFA) on HEp-2 (or ...