This odd arrangement, the authors found, influences the three-dimensional structure of the entire chromosome. “This is definitely a breakthrough within the field. We’ve been generating assemblies for ...

Scientists uncovered how whole-genome duplication emerges and remains stable over thousands of generations of evolution in the lab.

The echidna genome sequence provided here helps researchers trace the genetic events that led to this remarkable chromosomal ...

One of the key challenges of the modern genomics era is studying the thousands of genes in a single human cell at scale. To ...

"We are finding the 3D structure of the genome," said Satoshi Namekawa, professor of microbiology and molecular genetics at the University of California, Davis and senior author on one of the papers.

Each cell of the human body contains two meters of DNA. The whole secret lies in the intricate three-dimensional arrangement that allows DNA strands to be efficiently organized and compacted ...

Indeed, it is possible to reorder these ancestral syntenic fragments into their simplest arrangement, thereby recreating the ancestral genome (Figure 3). In the near future, with the availability ...

Researchers at the University of Tsukuba have developed a vector that integrates the Cre enzyme gene with the specific DNA ...

With the brittle star genome in hand, Marlétaz and his team investigated another important feature of the animal: their ability to regenerate. Like many other echinoderms, brittle stars can regenerate ...

Although this global arrangement allows insights into chromatin ... Yijun Ruan and Edwin Cheung from the Genome Institute of Singapore were interested in these functional relationships between ...