Spatial transcriptomics enables researchers to measure gene expression in tissue sections while preserving their spatial organisation. Unlike traditional RNA sequencing, which requires dissociating ...

Cerebral palsy is the most common cause of physical disability in children and young people in high-income countries, with a prevalence of 2.0–2.5 cases per 1000 live births.1 The physical ...

Staring episodes are a frequent reason for referral to paediatrics, as parents and teachers fear the possibility of seizures. Staring episodes in childhood are common and a challenging clinical ...

Table 6 Central cyanosis: cardiac causes (some cardiac conditions can be placed in more than one category) ...

Idiopathic intracranial hypertension (IIH) is a rare condition where intracranial hypertension is found in the context of normal brain parenchyma and no mass lesion, ventriculomegaly, underlying ...

What constitutes death has been discussed and debated throughout history. From a medical perspective, three sets of criteria are now recognised to diagnose death: somatic, circulatory and neurological ...

Handing over responsibility for patients has always been part of medical practice. Definitions emphasise transfer of responsibility to ensure patient safety and the available literature tends to ...

In recent times, paediatric pulmonary arterial hypertension management has been transformed to focus on disease modifying strategies that improve both quality of life and survival, rather than just ...

Review of: Roberts MY, Curtis PR, Sone BJ, Hampton LH. Association of Parent Training With Child Language Development: A Systematic Review and Meta-analysis. JAMA Pediatr 2019;173(7):671–680 Study ...

The aminoglycosides are broad-spectrum, bactericidal antibiotics that are commonly prescribed for children, primarily for infections caused by Gram-negative pathogens. The aminoglycosides include ...

A pilot project implementing pre-existing, free, health and well-being educational digital resources into the paediatric emergency department (PED) to promote healthy behaviours and reduce preventable ...

This guideline provides an evidence and expert consensus-based framework to assess and manage paediatric patients aged 4 weeks–18 years with a decreased conscious level of unknown cause.1 It was ...