NFL, The Seahawks and San Francisco 49ers
Digest more
Seattle Seahawks, NFC and 49ers
Digest more
Preview the Week 18 matchup between the Seattle Seahawks and San Francisco 49ers with predictions, odds, over/under, spread, betting lines and more.
8don MSN
Seahawks vs. 49ers prediction, odds, start time: Week 18 NFL Saturday picks by advanced model
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 18 on a 53-37 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.
Sam Darnold delivered a clean game manager performance, as his Seahawks dominated in every facet of play against the 49ers
The NFC West and the number one seed are on the line this Saturday night, and bettors could win big in this preview of the Seattle Seahawks and the San Francisco 49ers in this NFC West showdown.
In one of the most consequential games of the 2025 NFL season, the San Francisco 49ers host the Seattle Seahawks on Saturday night.
Sam Darnold and the Seahawks have won six in a row to take a one game lead into the final game of the regular season. Seattle is outscoring its opponents 29-18. Their stifling defense has allowed just 31 touchdowns through 16 games including just one last weekend in Charlotte to the Carolina Panthers in a 27-10 win.
49ers bold predictions for Week 18 as Brock Purdy and Christian McCaffrey power San Francisco’s playoff push and NFC top-seed hopes.
Brock Purdy threw a go-ahead 6-yard touchdown pass to Christian McCaffery late in the fourth quarter, San Francisco used a trick play on a TD toss from wide receiver Jauan Jennings, and the 49ers eliminated the defending Super Bowl champion Philadelphia Eagles with a 23-19 wild-card victory Sunday.