Glycolysis is an ancient metabolic activity ... its bioenergetic function important for growth and its signalling function crucial for cell fate decisions. When we inhibited glycolysis, we clearly saw ...

Historically, metabolism has been seen as a passive executioner of cell signaling. Previously we showed that a glucose metabolizing Hexosamine Biosynthesis Pathway (HBP) plays an important role in ...

Mitochondria play a crucial role in acquiring pluripotency and determining cell fate. The mitochondrial ... in somatic cell reprogramming, Nature Metabolism (2025). DOI: 10.1038 ...

Glycolysis is an ancient metabolic activity ... its bioenergetic function is important for growth and its signaling function crucial for cell fate decisions. When we inhibited glycolysis, we clearly ...

Cell biology revolves around a crucial concept: cells require nutrients for their survival, just as our bodies rely on nutrition (food) to support proper tissue and overall organismal functions. This ...

Historically, bone has been recognized primarily for its structural role in the body, but emerging research suggests that it ...

When these structures fail, cells struggle to function ... linked to other metabolic disorders. Understanding how mitochondria communicate with the nucleus to influence cell fate could open ...