rmdopen.bmj6d
Recognising the spectrum of scleromyositis: HEp-2 ANA patterns allow identification of a novel clinical subset with anti-SMN autoantibodies
Methods Twenty patients with seronegative scleromyositis diagnosed by expert opinion were analysed retrospectively for SSc features at myositis diagnosis and follow-up, and stratified based on HEp-2 ...
gut.bmj2d
Prevalence and clinical significance of isotype specific antinuclear antibodies in primary biliary cirrhosis
Methods: PBC specific ANA reactivity was tested by indirect immunofluorescence using HEp2 cells as substrate and individual Ig class (IgG, IgA, IgM) and IgG subclass (IgG1, IgG2, IgG3, IgG4) specific ...
Medscape4d
New Antinuclear Antibody Testing: Does it Cut Costs and Corners Without Jeopardizing Clinical Reliability?
Patients were diagnosed with SLE if they had had positive LE cell preparations and negative ANA test results. [1] There are only three reasons why the test is rarely performed today: it is labor ...
Harvard Medical School6d
Indirect Costs and Their Impact on Our Research Mission
The expenditures for these critical parts of the research enterprise are called indirect costs. They are substantial, and they are unavoidable, not least because it can be very expensive to build, ...