A research team has developed DeepCodon, a deep learning–based codon optimization tool that significantly improves heterologous protein expression in Escherichia coli while preserving functionally ...

Abstract: Co-optimizing mRNA sequences for both codon optimality and secondary structure is crucial for producing stable and efficacious mRNA therapeutics. Codon optimization, which adjusts nucleotide ...

Customizable expression systems are the future of bioprocessing, making cell-line development (CLD) the vital basis of production success. Artificial intelligence (AI) and machine learning (ML) will ...

This repository contains the infrastructure for generating a Shiny web application. The app is deployed via Shinyapps.io but can also be run locally. See App Setup ...

GenScript, a global leader in life sciences and biotechnology, successfully hosted an Open Day event at its Singapore facility on the 16th of April, welcoming more than 50 representatives from ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. DNA construction is central to testing biological hypotheses or ...

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1 Plant Genetic Engineering Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, India 2 Tecnologico de Monterrey, School of Engineering and Sciences, Centre of Bioengineering, ...

Introduction: Neurodegeneration and cancer present in comorbidities with inverse effects due to the expression of genes and pathways acting in opposition. Identifying and studying the genes ...