INDIANAPOLIS – Here is how the 49ers (11-4) graded in Monday night’s 48-27 win over the host Colts (8-7): PASS OFFENSE: A Brock Purdy threw a career-high five touchdown passes, including three on the ...

Two of the NFL's best headlined a Week 16 matchup with playoff implications, as Christian McCaffrey and the San Francisco 49ers defeated Jonathan Taylor and the Indianapolis Colts, 48-27, at Lucas Oil ...

George Kittle exited Week 16 game with an ankle injury, questionable to return. Before injury, Kittle had 7 catches, 115 yards, 1 touchdown, first 100-yard game of season. San Francisco 49ers won ...

Gambling content 21+. The New York Post may receive an affiliate commission if you sign up through our links. Read our editorial standards for more information. Week 16 gave us plenty of thrills ...

The 49ers clinched a playoff berth Sunday courtesy of the Pittsburgh Steelers. When the Steelers held on to beat the Detroit Lions 29-24 Sunday, it punched the 49ers’ ticket for the postseason with ...

Pearsall caught six passes for 96 yards in Sunday's win. Thearon W. Henderson / Getty Images SANTA CLARA, Calif. — The sequence was impossible to ignore. One day after shelving Brandon Aiyuk for the ...

The San Francisco 49ers will look to continue their push for the NFL playoffs when they host the Tennessee Titans on Sunday. San Francisco (9-4) is hot on the tails of the Los Angeles Rams and Seattle ...

The San Francisco 49ers today announced they have signed CB Isaiah Bolden to the team's practice squad. Bolden (6-2, 205) was originally drafted by the New England Patriots in the seventh round (245 ...

The law firm America First Legal (AFL) filed a civil rights complaint against the San Francisco 49ers with the U.S. Equal Employment Opportunity Commission (EEOC) for alleged discriminatory hiring ...

Pretty much everyone around the NFL assumes the San Francisco 49ers will trade quarterback Mac Jones in the offseason. But general manager John Lynch is pumping the brakes on the runaway speculation.

Nearly one week after he was at the center of a heated confrontation with an opponent, San Francisco 49ers wide receiver Jauan Jennings once again has drawn the ire of multiple members of another team ...