BMJ14h
N18 in median somatosensory evoked potentials: a new indicator of medullary function useful for the diagnosis of brain death
Dr Masahiro Sonoo, Department of Neurology, Teikyo University School of Medicine, Kaga 2–11–1, Itabashi-ku, Tokyo 173, Japan. Telephone 0081 3 3964 1211 ext 1911; fax 0081 3 3964 6397; email sonoom{at ...
BMJ13h
Prognostication and contemporary management of clinically isolated syndrome
Clinically isolated syndrome (CIS) patients present with a single attack of inflammatory demyelination of the central nervous system. Recent advances in multiple sclerosis (MS) diagnostic criteria ...
BMJ1d
The Goteborg MCI study: mild cognitive impairment is a heterogeneous condition
Background: Mild cognitive impairment (MCI) has been considered a transitional state between normal aging and dementia, characterised by memory impairment but normal general cognitive functioning.
BMJ2d
Deficient saccadic inhibition in Asperger’s disorder and the social-emotional processing disorder
1 Department of Psychiatry and the Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA 2 Department of Psychiatry, ...
BMJ2d
Hippocampal subfield atrophy of CA1 and subicular structures predict progression to dementia in idiopathic Parkinson’s disease
Background Global hippocampal atrophy is a hallmark of Alzheimer’s dementia and has been similarly reported in Parkinson’s disease dementia (PDD). However, there is limited literature on the ...
BMJ10d
Complete Epstein-Barr virus seropositivity in a large cohort of patients with early multiple sclerosis
Objective To determine the prevalence of antibodies to Epstein-Barr virus (EBV) in a large cohort of patients with early multiple sclerosis (MS). Methods Serum samples were collected from 901 patients ...
BMJ10d
Ultra-high-dose methylcobalamin in amyotrophic lateral sclerosis: a long-term phase II/III randomised controlled study
Objective To evaluate the efficacy and safety of intramuscular ultra-high-dose methylcobalamin in patients with amyotrophic lateral sclerosis (ALS). Methods 373 patients with ALS (El Escorial definite ...
BMJ11d
Data-driven evolution of neurosurgical gene therapy delivery in Parkinson’s disease
Loss of nigrostriatal dopaminergic projection neurons is a key pathology in Parkinson’s disease, leading to abnormal function of basal ganglia motor circuits and the accompanying characteristic motor ...
BMJ5d
Effectiveness of early cycles of fast-acting treatment in generalised myasthenia gravis
Background Early fast-acting treatment (EFT) is the aggressive use of fast-acting therapies such as plasmapheresis, intravenous immunoglobulin and/or intravenous high-dose methylprednisolone (IVMP) ...
BMJ1d
Assessment of the severity of head injury.
Ranking of head injuries by severity is an essential part of clinical management, of prognosis, of treatment trials, and of legal assessment for compensation. Various methods of assessing severity are ...
BMJ5d
The non-linear relationship between nerve conduction velocity and skin temperature.
Median motor and sensory nerves were examined in 20 healthy subjects. Superficial stimulating and recording electrodes were used, and the nerves were examined at natural skin temperature, after ...
BMJ4d
Recovery patterns and long term prognosis for axonal Guillain–Barré syndrome
Background: Little is known about the long term prognosis for patients the severe acute motor axonal neuropathy (AMAN) form of Guillain–Barré syndrome (GBS), unlike those with acute inflammatory ...