Dipeptidyl peptidase (DPP)-4 is a complex enzyme that exists as a membrane-anchored cell surface peptidase that transmits intracellular signals via a short intracellular tail and as a second smaller ...

LA JOLLA, CA – October 31, 2012 – Scientists at The Scripps Research Institute (TSRI) have discovered the first selective inhibitors of an important set of enzymes. The new inhibitors, and chemical ...

SGLT2 inhibitors are medications designed to help manage blood sugar in people living with type 2 diabetes. Learn more about the different types, as well as the benefits and side effects.

Research has shown that angiotensin converting enzyme (ACE) inhibitors help manage diabetic nephropathy-related issues. They can also slow the progression of diabetic nephropathy in some people.

Atrial fibrillation, or AFib, is the most common heart rhythm disorder. With AFib, the beating of the upper chambers of your heart (the atria) becomes irregular, and blood has a harder time reaching ...

In a new study published in Science Signaling titled, “Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice,” researchers from ...

A near-universal way to measure enzyme inhibition. ScienceDaily. Retrieved December 20, 2025 from www.sciencedaily.com / releases / 2018 / 03 / 180301103613.htm McGill University. "A near-universal ...

Recent evidence suggests that natural products are much more than simply agents of “microbial warfare” and actually play critical roles in bacterial pathogenesis and communication. In particular, ...

An illustration shows the structure of an inhibitor bound to the active site of membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase. An inhibitor bound to the active site of ...