Monocarboxylate transporters (MCTs) are integral membrane proteins that mediate proton-coupled shuttling of small metabolites such as lactate, pyruvate and short-chain fatty acids across cellular ...

In a study published in Nature on January 28, a research team led by Eric H. Xu (Xu Huaqiang) from the Shanghai Institute of Materia Medica of the Chinese Academy of Sciences, along with Ma Xiong from ...

This study systematically elucidates the multifunctional transport properties and structural basis of BTR1, a member of the SLC4 family. Using cryo-electron microscopy (cryo-EM) and electrophysiology, ...

Bile acids are essential for digestion, metabolism, and hormonal signaling. Their circulation between the liver and intestine, known as enterohepatic circulation, depends on a coordinated network of ...