Overview: Tamoxifen is commonly used to treat certain types of breast cancer. It is also used to lower your risk of invasive breast cancer and keep some breast cancers from coming back. It blocks ...
Abstract Purpose We examined the feasibility of using CYP2D6 genotyping to determine optimal tamoxifen dose and investigated whether the key active tamoxifen metabolite, endoxifen, could be increased ...
Breast cancer treatment has increasingly integrated pharmacogenomic insights to tailor therapies according to patients’ genetic profiles, thereby optimising treatment outcomes and minimising adverse ...
Avoidance of concomitant medications known to decrease CYP2D6 activity might improve outcomes for patients with the wild-type genotype, but we are left with the question of what the best treatment ...
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