For example, the discovery of phosphorylation on tyrosine, a modification that was previously thought to occur exclusively on serine and threonine residues, was aided in part by extremely active ...

TOR is an atypical serine/threonine protein kinase that is highly conserved in living organisms. TOR serves as a key signaling integrator that controls diverse cellular processes such as organ ...

Protein phosphorylation is a covalent post-translational modification event that is essential for regulation and maintenance of most biological processes in eukaryotes 1. Conventionally ...

Several recent Atavistik Bio Inc. patents describe substituted aminopyridine compounds acting as RAC-α serine/threonine-protein kinase (AKT1; PKBα) inhibitors, particularly AKT1 (E17K mutant) reported ...