New research sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...

Cancer cells often survive treatment by fixing the DNA damage that therapy is meant to cause. Researchers found that UNI418 ...

Similar to the way DNA damage can contribute to human diseases such as cancer, it can also disrupt growth, development and ...

Homologous recombination is a DNA repair mechanism that counteracts double-stranded breaks in DNA. Researchers at Kindai University have recently revealed how the Sae2 protein coordinates with the ...

DNA is the blueprint of the human body. However, tens of thousands of DNA lesions occur in our bodies every day. In ...

DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...

Two teams of researchers have uncovered microscopic details of how a protein called photolyase uses light to repair DNA. The discovery could help develop sustainable technologies for chemical ...

A new fluorescent sensor is giving scientists an unprecedented view of how cells respond to DNA damage, capturing the repair process as it unfolds in real time. The tool, developed at Utrecht ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal metabolic processes or external stressors such as radiation or chemical ...

A new study suggests that a specific "longevity gene" may help protect the brain from the effects of aging, including Alzheimer’s disease. The APOE gene (short for apolipoprotein E) helps the body ...

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human ...