Effective protein characterization depends on the precise isolation and fragmentation of peptide ions within the mass spectrometer, typically coupled with liquid chromatography (LC-MS/MS). In a ...

Mass spectrometry is already a powerful tool for determining what kind and how many molecules are present in a given sample. But most instruments still analyze their molecules one or just a few at a ...

The prototype ion trap contains hundreds of inlets and outlets, mimicking how biology moves things into and out of cell nuclei. Credit: Lori Chertoff/The Rockefeller University When J. J. Thomson ...

Day 1 of the annual meeting of the American Society for Mass Spectrometry (ASMS; NM, USA) has been jam-packed with press conferences from the biggest names in mass spectrometry, and I have been to ...

At the University of Oxford, Justin Benesch studies assemblies made between proteins called molecular chaperones and the proteins they protect in cells. These assemblies slow the formation of amyloid ...

Single-cell proteomics (SCP) by mass spectrometry (MS) has evolved into a powerful technique to investigate cellular heterogeneity with increasing coverage and throughput. To tackle the challenge of ...

Oligonucleotide mapping via liquid chromatography with UV detection coupled to tandem mass spectrometry (LC-UV-MS/MS) was recently developed to support development of Comirnaty, the world’s first ...

Just how far mass spectrometry—the use of tools measuring the mass-to-charge ratio (m/z) of one or more molecules present in a sample—has progressed over the past century can be seen in a new exhibit ...

Beijing Zhongke Journal Publising Co. Ltd. The traditional method for detecting dissolved gases in the deep sea is offline detection, which combines pressure sampling with laboratory analysis. This ...