“The problem of selectivity has turned the industry’s attention towards discovering and developing therapeutic antibodies targeting ion channels,” explained Paul Colussi, VP of research at ...

Today it seems self-evident that neurons make their electrical signals by opening gates of water-filled pores (ion channels) in the plasma membrane. But it was not always so. Remarkably, pore ...

Our laboratory uses a combination of structural biology and biophysical techniques to discover how ion channels and membrane-embedded enzymes function at the atomic level. The proteins we study are ...

Our lab studies the physiology, pharmacology and biophysics of ion channels. Ion channel proteins form ion-selective pores within cell membranes and in the heart they establish and maintain normal ...

A Cambridge-based biotechnology firm developing antibody-based KnotBody drugs for ion channel- and G protein-coupled receptor (GPCR)-driven diseases, has raised £58m in a Series A financing.

Maxion Therapeutics Raises $72 million (£58 million) in an Oversubscribed Series A Financing to Advance its KnotBody® Pipeline and Platform Financing led by General Catalyst with additional investment ...