Type I allergy, an IgE antibody triggered hypersensitivity disease, represents a common public health problem affecting about one third of the world´s population. Upon exposure to allergens, IgE ...

By simulating allergic reactions in a controlled environment, the test provides functional insights into IgE-mediated allergies. In the Hoxb8 MAT, mast cells are exposed to serum samples from ...

These pain responses were also dependent on mast cells (specialized white blood cells), local IgE antibodies and STAT6 signaling, which plays a role in cell proliferation. When these mice were ...

A new anti-HER2 IgE antibody potentially offers new therapy options for treatment-resistant breast and ovarian cancers.

MiR-126-5p down-regulation alleviates the inflammatory response of allergic rhinitis in children via inhibiting HIPK2/NF-κB ...

The IgE stimulates specialized cells in the airways called mast cells to produce histamines, which cause the familiar symptoms of seasonal allergies. This is the same process that causes allergies ...

WATERTOWN, Mass.--(BUSINESS WIRE)--Seismic Therapeutic, Inc., the machine learning immunology company, today announced the presentation of preclinical data for its immunoglobulin E (IgE) protease ...