A diagram of the DRT3 system, showing Drt3a in yellow and Drt3b in blue. (Hyunbin Lee) Scientists have just discovered an ...

From synthetic biology and gene therapy to data storage and biofuel production, the demand for synthetic DNA is rising. (1) Chemicals remove the 5’-hydroxyl protecting group. The nucleosides are rich ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

DNA synthesis is vital to several processes in biopharmaceutical innovation, including the development of gene therapies, CRISPR gene editing, antisense oligonucleotides and RNA therapies. The need ...

Thanks to a serendipitous discovery and a lot of painstaking work, scientists can now build biohybrid molecules that combine the homing powers of DNA with the broad functional repertoire of proteins - ...

Illinois biochemistry professor Satish Nair and his colleagues discovered a new class of DNA-protein hybrids and determined the mechanisms by which they are formed in bacterial cells. The findings ...