New research combines two powerful imaging techniques to study the complete structure of a common aGPCR, including how its long and complex extracellular region interacts with the transmembrane region ...

Triggering receptors expressed on myeloid cells (TREMs) are a cell surface receptor family found on granulocytes, monocytes, macrophages, and dendritic cells—as well as other myeloid cells in general.

Recently these monocyte-derived alveolar macrophages, or Mo-AMs, were identified as key drivers of lung fibrosis disease progression. However, the mechanisms of their pro-fibrotic behavior and ...

Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead ...

BIRMINGHAM, Ala. – Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages — the white blood cells that defend the body by killing microbes, ...