Bacteria coordinate DNA replication, cell growth and morphological changes via a tightly regulated cell cycle. Central to this process is a network of signalling pathways, transcription factors and ...
The cell cycle is governed by a network of surveillance mechanisms that detect DNA lesions and coordinate repair with progression through G1, S, G2 and M phases. Central to this system are sensor ...
The review emphasizes how breakthroughs in understanding the molecular mechanisms of cell cycle regulation have paved the way for the development of targeted anti-cancer agents. Notably, inhibitors of ...
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