Future Neurology. 2008;3(6):683-704. In a recent meta-analysis, CADASIL patients were reported to also suffer from neuromuscular symptoms, weakness, wasting, reduced/exaggerated tendon reflexes, ...

A new study from Karolinska Institutet shows that damage to small blood vessels in the hereditary disease CADASIL may disrupt important brain functions in the hippocampus, a region involved in memory.

CADASIL, an inherited disease caused by mutations in the NOTCH3 gene, damages the brain’s small blood vessels, leading to strokes, cognitive decline, and early dementia. Despite decades of research, ...

Patients with the CADASIL* form of vascular dementia may have several measures of their executive function** improved by taking donepezil. But the drug did not improve the patients' cognitive score, ...

Please provide your email address to receive an email when new articles are posted on . The off-label use of donepezil did not improve cognitive ability scores in patients with an early onset form of ...

The Mount Sinai Health System has received an $8 million grant from DataPhilanthropy to fuel urgently needed research into CADASIL, a genetic disease associated with changes to small blood vessels ...

A devastating vascular disorder of the brain called CADASIL, which strikes young adults and leads to early dementia, often is misdiagnosed as multiple sclerosis, Loyola University Health System ...

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited cerebrovascular disease characterized by brain infarcts, cognitive decline and ...

Known as cerebral autosomal dominant arteriopathy with sub-cortical infarcts and leukoencephalopathy (CADASIL), the genetic disorder generally leads to vascular dementia. Inherited from a parent, the ...

Cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy (CADASIL) is the most common hereditary subcortical vascular dementia. It is caused by the defective NOTCH3 ...