and allowed to compete for hybridization sites on either metaphase chromosomes (left) or an array of BAC (bacterial artificial chromosome) clones that represent thousands of small DNA segments ...

Within each HAC, the researchers designed sequences to bind centromeric proteins, which ensured that daughter cells would inherit the chromosome when the original cell divided. Specifically, they ...

Purpose: To illustrate the use of bacterial artificial chromosome (BAC) clone panels for molecular cytogenetic analysis of complex chromosome rearrangements (CCRs). Methods: High resolution ...