Potent new drug has all the power of nature's strongest antibiotic, without the toxicity Mandimycin is a polyene macrolide within the polyene class of antifungals. Aside from polyenes, there are ...

Resistance is nowadays the rule rather than the exception for the four currently available antifungal classes, making it difficult - if not impossible – to treat many invasive fungal infections.

Brexafemme is the first antifungal in what is only the fourth antifungal class to reach the market, and has data showing activity in three of four MDR infections on the World Health Organization ...

By contrast, other antifungals in this class such as amphotericin B (AmB) typically have one glycosyl group. Mandimycin is part of the family of glycosylated polyene macrolides that has provided ...

F2G is a biotech company that specializes in developing therapies to treat invasive fungal infections through a novel class of antifungal agents called the orotomides. There are at least 5 million ...