Los Angeles is a 4.5-point favorite in the latest Chargers vs. Dolphins odds from SportsLine consensus, while the over/under for total points scored is 43.5. The Chargers are -227 money line favorites (risk $227 to win $100),

While the Chargers will be missing a pair of starting offensive linemen and their top two running backs, they're still favored against a Miami team facing a crossroads. Another loss for the Dolphins could further derail the 2025 season and perhaps set the stage for major change in leadership.

Spread: NBC Sports Bet is leaning towards a play ATS on the Miami Dolphins at +4.5. Rotoworld has you covered with all the latest betting info & tools for NFL with player news, game predictions, player props, futures, and trends!

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